Our Perspectives
THREAD Blog
Increasing Diverse Clinical Populations: Geography
Decentralized clinical trials (DCTs) and the digital approaches they employ bring research opportunities to a more diverse geographic population. Find out more.
Unlocking the Patient’s Voice – The Benefits of Patient Co-Creation in Clinical Research
While it may seem simple and obvious, one answer to making research work better for patients is through listening to them. This goes beyond simply asking them questions and recording responses (passive listening), but engaging in mindful and intentional active listening, often aided by technology, to capture insights that can lead directly to solutions that improve how clinical studies work.
Ultra-Rare Disease and Clinical Research– Different Approaches for Unique Studies
In a previous blog, we discussed ultra-rare diseases and the unique research challenges they pose to the development of new therapies. The nature of rare and ultra-rare disease means that drug development pathways and the types of studies commonly conducted can differ from the pathways and approaches used for more common diseases.
Increasing Diverse Clinical Populations: Sex
In Part I, we’ll look at how research can better address often overlooked gender based differences as an underappreciated variable in the evidence generated in the clinical development lifecycle and why extrapolation of results from one gender to another is objectionable.
How to Give Your Clinical Trial Participants More Control, Convenience & Comfort
Some estimates indicate 80% of trials are delayed due to participant retention challenges. However, sponsors and CRO’s can curb this attrition by focusing their trials on patient comfort, convenience, and by ensuring they feel in control of their participation. Adopting a truly patient-centered study design means acknowledging that every patient comes in with differing needs surrounding these three tenets and addressing them throughout trial design and execution.